Australian Open - Andy Murray, Serena Williams
The world number five has a tough draw and while the Australian Open odds
don't make him the favourite for the title he is ready to make the breakthrough and win his first Grand Slam.
A four-time Australian Open winner, Serena has started the season in determined mood after the trauma of last year's US Open, which spells trouble for her rivals.
French Open - Rafael Nadal, Justine Henin
Nadal has taken time to recover from 2009's injury troubles and personal issues, but he will be back to his best at Roland Garros.
Henin was once nearly as dominant as Nadal in Paris, winning four titles in five years. Clay is Serena's weakest surface and Henin will be ready to take advantage.
Wimbledon - Andy Roddick, Serena Williams
Roddick did everything but win last year's event, losing an epic final to Roger Federer, so his new-look game is capable of ending his long Grand Slam drought.
Serena had the better of the traditional family showdown at Wimbledon last year and I expect her to be in better form than Venus (and everyone else for that matter) again this time around.
US Open - Roger Federer, Elena Dementieva
Federer's five year winning streak at Flushing Meadows was ended by Juan Martin del Potro last year, but the New York hard courts remain the Swiss Legend's domain.
At Wimbledon last year the Russian showed she is ready to make the step up, narrowly losing an epic semi-final to Serena Williams. She can go one better than she did at the 2004 US Open, when she reached the final.
Davis Cup - Spain
Spain have won the last two Davis Cups and thrashed Czech Republic 5-0 in the 2009 final. With Nadal and Fernando Verdasco in their ranks, as well as David Ferrer and Tommy Robredo, they will again be hard to beat especially at home on clay.
Fed Cup - Russia
Russia have won four of the last six Fed Cups and have enough strength in depth - six players in the current top 20 - to justify their status as the strongest nation in the women's game.
Meanwhile, in horse racing betting
news the odds for this year's Cheltenham Festival are really starting to hot up and could be worth keeping an eye on.