RAWALPINDI, Pakistan (CNN) -- Pakistan's former Prime Minister Benazir Bhutto was assassinated Thursday in the wake of a suicide bombing that killed at least 14 of her supporters, doctors, a spokesman for her party and other officials said.
Bhutto suffered bullet wounds in the aftermath of the bomb attack, TV networks were reporting.
Police warned citizens to stay home as they expected rioting to break out in city streets as a shocked Pakistan absorbed the news of Bhutto's assassination.
Video of the scene just moments before the explosion showed Bhutto stepping into a heavily-guarded vehicle to leave the rally.
Bhutto was rushed to Rawalpindi General Hospital -- less than two miles from the bombing scene -- where doctors pronounced her dead.
Former Pakistan government spokesman Tariq Azim Khan said while it appeared Bhutto was shot, it was unclear if the bullet wounds to her head and neck were caused by a shooting or if it was shrapnel from the bomb.
The bomber detonated as he tried to enter the rally where thousands of people gathered to hear Bhutto speak, police said.
The number of wounded was not immediately known. However, video of the scene showed ambulances lined up to take many to hospitals.
he attack came just hours after four supporters of Pakistan's former Prime Minister Nawaz Sharif died when members of another political party opened fire on them at a rally near the Islamabad airport Thursday, Pakistan police said.
Several other members of Sharif's party were wounded, police said.
Bhutto was participating in the parliamentary election set for Jan. 8, hoping for a third term as prime minister.
A terror attack targeting her motorcade in Karachi killed 136 people on the day she returned to Pakistan after eight years of self-imposed exile.
CNN's Mohsin Naqvi, who was at the scene of both bombings, said Thursday's blast was not as powerful as that October attack.
Thursday's attacks come less than two weeks after Pakistan President Pervez Musharraf lifted an emergency declaration he said was necessary to secure his country from terrorists.