Yeah it's interesting how you have both Djokovic and Murray losing In the quarters .
I'd put money on Nadal losing earlier then Djokovic or Murray ,Think about it . Nadal has players in his draw that can beat him and match up well against him . then he could face Roger if they both make it and they've never played at the US open so we don't know how that would go and you have to add that if they both get there , one might have had tough matches on route to the quarters the other might not have .
I'm picking either Roger or Nadal to win . there draw is so easy compared to the top that if one of them makes it to the final they'll win .
I agree with most of that, except I favor Andrey Kuznetsov to beat Sela and Tipsy and make R32, as well as Djokorray semi, with Novak coming out on top. The final's a tossup, leaning towards Nadal though.