The only thing that will stop Federer from winning the US Open this year is injury.
None of those still standing can match his play this year on hard court.
People predicting/hoping for a Nadal/Federer final are probably going to be disappointed.
#1 RAFA is one of my players, but he simply can't return on hard courts these days to save his life. He looks frightened to death and when he makes a return it too often doesn't go past the service line. He stands so far back these days, the line umpires could probably reach the ball before he could if they had racquets. Besides he and Uncle Toni have already said they don't want to play Federer in another final off clay. RAFA's serve isn't good enough to compensate for his return problems, and he will get broken too often against a player with belief. Look for an early exit from New York for Clay Warrior unless he has a fantastic draw.
Djokovic, Wawrinka, and Nishikori are gone for the year.
Murray hasn't played since Wimbledon and who knows if he will play in New York. Even if he does, there is little doubt he will be under-cooked.
That leaves the rest. The hot young players like Zverev and Kyrgios still have much to prove in majors. They will be fortunate to make a SF.
Del Potro still isn't up near his best match after match, though he can be a spoiler. Cilic is doubtful. Raonic doesn't seem a threat this year. Dimitrov is too inconsistent. Thiem is better on clay. Querrey might be the best American hopeful as Isner could be tired from his efforts, but one can't see either going further than the QF.
Probably Berdych is playing the best of the rest, but his misfortune has been to meet Federer of late and has been unable to win sets. The best playing Spaniard on hard courts of late, David Ferrer, is probably playing well enough again to reach a QF depending on the draw. The French Armada? Tsonga, Monfils, Gasquet, and Simon are just too weak (someone feed Simon please) to go all the way. Pouille hasn't been able to progress. Paire is on some other planet. Belgian Goffin is not strong enough.
Did I miss anyone significant?
One simply can't look past Roger for his 94th title and 3rd major victory of the year as long as he remains healthy.