Sam doesn't want to play tennis right now, and has been completely awful since the summer of 2010. He flat out doesn't care, as he's shown, and as he's said. Lacko was average at best and that's all it took.
Really opens up the draw for I think Hewitt to breeze through that section, or potentially Del Potro.
As you said, Querrey was never going to be a factor anyway, so it hardly makes much impact on the section, even.