I don't think this defeat is worrying in regard with Nadal's health. His mind was never on Wimbledon ever since Euro2012 started. He has arrived today in Kiev
to watch the final live accompanied by Pau Gasol and Fernando Alonso. I don't think Rafa is disappointed he lost at SW19.
He can do with his life whatever he likes but in this case he should have not entered Wimbledon at all. He should have come up with an injury/exhaustion excuse and just pass on the tournament GS or not.
I find his focus not being that much on tennis anymore, maybe he wants to just enjoy life - go fishing, play golf, shooting ads, spending time on his hobbies like football etc. No problem but if that is so just leave the game and tell your fans you have new priorities.
I on my part do not expect from Rafa to win anything significant anymore. He'll probably keep hanging in, reaching a couple of SF/F and not winning a title. For me Olympics and WTF are of no importance, meaningless titles. But USOpen is quite different story. Unfortunately he's not winning it again. IMO he will retire after this season.