Roger Federer (SUI) vs. Bye
Carlos Berlocq (ARG) vs. Qualifier
Kevin Anderson vs. Juan Carlos Ferrero (SPA)
Alex Bomogolov (USA) vs. Gael Monfils (FRA) John Isner (USA) vs. Philipp Kohlschreiber (GER)
Andreas Seppi (ITA) vs. Denis Istomin (UZB)
Stanislas Wawrinka vs. Qualifier
 Janko Tipsarevic (SRB) vs. Bye
PARIS -- This, then, is who John Isner is for now: The Marathon Man of Tennis, the guy who plays and plays and plays, for hours on end, until the last set seems interminable.
At Wimbledon two years ago, he won 70-68 in the fifth, the longest set and match in tennis history. At Roland Garros on Thursday, as afternoon gave way to evening, the 10th-seeded American lost 7-6 (2), 4-6, 4-6, 6-3, 18-16 to Paul-Henri Mathieu of France in the second round, a 5-hour, 41-minute test of stamina and attention span.